Course Description: Immunology is a fascinating, but complex and rapidly changing field. In this course you will learn about the molecular and cellular basis for the human immune system and how it works. You will also see what happens when it doesn't work, and how scientists are using knowledge of immune response mechanisms to prevent and cure diseases. The class has two components, 1) Lectures and 2) Specific topic study. Each student will be required to conduct a bibliographic search on a specific topic chosen among the proposed topics, and write a report (5-6 pages, single space). Toward the end of the quarter, each student will make a power point presentation (15-20 min) on this specific topic and lead a discussion. Your participation and extensive discussion are critical for success of this component of the class. Therefore, your participation in the discussion will be graded. Course Objectives: At the end of this course students will be able to: • Recognize the significance of the immune system in combating infection and disease. • Describe the factors influencing immunogenicity. • Provide an overview of the types of cell interactions and molecules required for specific immunity. • Know the structure and function of cell surface molecules involved in immune cell interactions. • Know the modern approaches to immunization. • Know the changes in cellular characteristics due to malignancy. • Know the major primary immunodeficiencies and their features.